• Cold Ischemia >4 Hours Increases Heart Transplantation Mortality. An Analysis of the Spanish Heart Transplantation Registry 

      Valero-Masa, María Jesús; González-Vílchez, Francisco; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Manito-Lorite, Nicolás; Sobrino-Márquez, José Manuel; Gómez-Bueno, Manuel; Delgado Jiménez, Juan Francisco; Pérez-Villa, Félix; Brossa-Loidi, Vicens; Arizón-del-Prado, José M.; Díaz-Molina, Beatriz; Fuente Galán, Luis de la; Portolés-Ocampo, Ana; Garrido-Bravo, Iris P.; Rábago, Gregorio; Martínez-Sellés, Manuel (Elsevier, 2020-06-20)
      [Abstract] Background. Cold ischemia time (CIT) has been associated to heart transplantation (HT) prognosis. However, there is still uncertainty regarding the CIT cutoff value that might have relevant clinical ...
    • Conversion from immediate-release tacrolimus to prolonged-release tacrolimus in stable heart transplant patients: a retrospective study 

      González-Vílchez, Francisco; Delgado Jiménez, Juan Francisco; Palomo, Jesús; Mirabet, Sonia; Díaz Molina, Beatriz; Almenar-Bonet, Luis; Arizón-del-Prado, José M.; Rangel-Sousa, Diego; Pérez-Villa, Félix; Garrido, Iris P.; Fuente, Luis de la; Gómez-Bueno, Manuel; Sanz-Julve, Marisa; Crespo-Leiro, María Generosa (Elsevier, 2019-07-01)
      [Abstract] Background Lifelong adherence with post-transplant immunosuppression is challenging, with nonadherence associated with greater acute rejection (AR) risk. Methods This retrospective study evaluated conversion ...
    • Evaluation of humoral immunity profiles to identify heart recipients at risk for development of severe infections: a multicenter prospective study 

      Sarmiento, Elizabeth; Jaramillo, María; Calahorra, Leticia; Fernández-Yáñez, Juan; Gómez-Sánchez, Miguel; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Almenar-Bonet, Luis; Cebrián, Mónica; Rábago, Gregorio; Levy, Beltrán; Segovia-Cubero, Javier; Gómez-Bueno, Manuel; López, Javier; Mirabet, Sonia; Navarro, Joaquín; Rodríguez-Molina, Juan José; Fernández-Cruz, Eduardo; Carbone, Javier (Elsevier, 2017)
      [Abstract] BACKGROUND: New biomarkers are necessary to improve detection of the risk of infection in heart transplantation. We performed a multicenter study to evaluate humoral immunity profiles that could better enable ...
    • Health‐related quality of life, social support, and caregiver burden between six and 120 months after heart transplantation: a Spanish multicenter cross‐sectional study 

      Delgado Jiménez, Juan Francisco; Almenar-Bonet, Luis; González-Vílchez, Francisco; Arizón-del-Prado, José M.; Gómez-Bueno, Manuel; De la Fuente-Galán, Luis; Brossa-Loidi, Vicens; Fernández-Yáñez, Juan; Díaz Molina, Beatriz; Pascual Figal, Domingo A.; Lage-Gallé, Ernesto; Sanz-Julve, Marisa; Manito-Lorite, Nicolás; Crespo-Leiro, María Generosa (Wiley, 2015-06-15)
      [Abstract] A multicenter cross-sectional study was conducted to determine the current heart transplant (HTx) outcomes in Spain. Clinical and functional status, health-related quality of life (HRQoL), social support, and ...
    • Incidence and prognosis of colorectal cancer after heart transplantation: data from the spanish post-heart transplant tumor registry 

      Sagastagoitia-Fornie, Marta; Morán-Fernández, Laura; Blázquez-Bermejo, Zorba; Díaz-Molina, Beatriz; Gómez-Bueno, Manuel; Almenar-Bonet, Luis; López Granados, Amador; González-Vílchez, Francisco; Mirabet-Pérez, Sonia; García-Romero, Elena; Sobrino-Márquez, José Manuel; Rábago Juan-Aracil, Gregorio; Castel-Lavilla, María Ángeles; Blasco-Peiró, Teresa; Garrido-Bravo, Iris P.; De la Fuente-Galán, Luis; Muñiz, Javier; Crespo-Leiro, María Generosa (Frontiers, 2023-05)
      [Abstract] In this observational and multicenter study, that included all patients who underwent a heart transplantation (HT) in Spain from 1984 to 2018, we analyzed the incidence, management, and prognosis of colorectal ...
    • Malignancy following heart transplantation: differences in incidence and prognosis between sexes – a multicenter cohort study 

      Minguito‐Carazo, Carlos; Gómez-Bueno, Manuel; Almenar‐Bonet, Luis; Barge-Caballero, Eduardo; González-Vílchez, Francisco; Delgado-Jiménez, Juan F.; Arizón-del-Prado, José M.; Sousa-Casasnovas, Iago; Mirabet, Sonia; González-Costello, José; Sobrino-Márquez, José Manuel; Pérez-Villa, Félix; Díaz Molina, Beatriz; Rábago, Gregorio; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; García-Guereta, Luis; Camino, Manuela; Albert-Brotons, Dimpna C.; Muñiz, Javier; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-01-22)
      [Abstract] Male patients are at increased risk for developing malignancy postheart transplantation (HT); however, real incidence and prognosis in both genders remain unknown. The aim of this study was to assess differences ...
    • Mechanical circulatory support in severe primary graft dysfunction: peripheral cannulation but not earlier implantation improves survival in heart transplantation 

      Olivella, Aleix; Almenar-Bonet, Luis; González-Vílchez, Francisco; Díez-López, Carles; Díaz-Molina, Beatriz; Blázquez-Bermejo, Zorba; Sobrino-Márquez, José Manuel; Gómez-Bueno, Manuel; Garrido-Bravo, Iris P.; Barge-Caballero, Eduardo; Farrero-Torres, Marta; García-Cosío, María Dolores; Blasco-Peiró, Teresa; Pomares-Varó, Antonia; Muñiz, Javier; González-Costello, José (Elsevier, 2023-03-15)
      [Abstract] Background. Primary graft dysfunction (PGD) still affects 2-28% of heart transplants (HT). Severe PGD requires mechanical circulatory support (MCS) and is the main cause of death early after HT. Earlier initiation ...
    • Preoperative toxoplasma gondii serostatus does not affect long-term survival of cardiac transplant recipients: analysis of the Spanish Heart Transplantation Registry 

      Barge-Caballero, Eduardo; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Brossa-Loidi, Vicens; Rangel-Sousa, Diego; Gómez-Bueno, Manuel; Farrero-Torres, Marta; Díaz-Molina, Beatriz; Delgado-Jiménez, Juan F.; Martínez-Sellés, Manuel; López-Granados, Amador; De la Fuente-Galán, Luis; González-Costello, José; Garrido-Bravo, Iris P.; Blasco-Peiró, Teresa; Rábago, Gregorio; González-Vílchez, Francisco (Elsevier, 2017-10-07)
      [Abstract] Background. It's unclear whether pre-transplant T. gondii seropositivity is associated with impaired survival in heart transplant recipients. Objectives. To test the above-mentioned hypothesis in the Spanish ...
    • Pulmonary vascular remodeling and prognosis in patients evaluated for heart transplantation: insights from the OCTOPUS-CHF study 

      Martínez-Solano, Jorge; Gutiérrez-Ibañes, Enrique; Ortiz-Bautista, Carlos; García-Cosío, María Dolores; Sarnago-Cebada, Santiago; Díaz-Molina, Beatriz; Pascual, Isaac; Oteo-Domínguez, Juan Francisco; Gómez-Bueno, Manuel; Calviño-Santos, Ramón; Crespo-Leiro, María Generosa; Gómez-Hospital, Joan Antoni; Díez-López, Carles; García-Lara, Juan; Garrido-Bravo, Iris P.; de la Fuente-Galán, Luis; López-Díaz, Javier; Mirabet-Pérez, Sonia; Martínez-Sellés, Manuel (MDPI, 2022-12-06)
      [Abstract] Objective: In patients with advanced heart failure, the intravascular optical coherence tomography (OCT) of subsegmental pulmonary artery measurements is correlated with right heart catheterization parameters. ...
    • Renal Function Impact in the Prognostic Value of Galectin-3 in Acute Heart Failure 

      Crespo-Leiro, María Generosa; Caravaca Pérez, Pedro; González-Juanatey, J. R.; Nuche, Jorge; Matute-Blanco, Lucía; Serrano, Isabel; Martínez-Selles, Manuel; Vázquez García, Rafael; Martínez-Dolz, Luis; Gómez-Bueno, Manuel; Pascual Figal, Domingo; García-Osuna, Álvaro; Ordóñez-Llanos, Jordi; Cinca Cuscullola, Juan; Guerra, José M.; Delgado, Juan F. (Frontiers, 2022-04)
      [Abstract] Introduction: Galectin-3 (Gal-3) is an inflammatory marker associated with the development and progression of heart failure (HF). A close relationship between Gal-3 levels and renal function has been observed, ...
    • Results of heart retransplantation: subanalysis of the Spanish Heart Transplant Registry 

      Salterain-González, Nahikari; Rábago Juan-Aracil, Gregorio; Gómez-Bueno, Manuel; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Arizón del Prado, José María; García-Cosío, María Dolores; Martínez-Sellés, Manuel; Mirabet-Pérez, Sonia; Sobrino-Márquez, José Manuel; González-Costello, José; Pérez-Villa, Félix; Díaz-Molina, Beatriz; de la Fuente-Galán, Luis; Blasco-Peiró, Teresa; Garrido, Iris P.; García-Guereta Silva, Luis; Gil-Villanueva, Nuria; Gran, Ferrán; González-Vilchez, Francisco (Elsevier, 2021-07-10)
      [Abstract] Introduction and objectives: Heart retransplantation (ReHT) is controversial in the current era. The aim of this study was to describe and analyze the results of ReHT in Spain. Methods: We performed a ...
    • Spanish heart transplant registry. 33rd official report of the Heart failure Association of the Spanish Society of Cardiology 

      González-Vílchez, Francisco; Gómez-Bueno, Manuel; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Arizón del Prado, José M.; Blázquez-Bermejo, Zorba; Delgado-Jiménez, Juan F.; Antonio-Ferrer, Marta de; Sobrino-Márquez, José M.; García-Romero, Elena (Elsevier, 2022-07-16)
      [Abstract] Introduction and objectives: This report updates the annual data of the Spanish Heart Transplant Registry with the procedures performed in 2021. Methods: We describe the clinical profile, therapeutic ...
    • Spanish Heart Transplant Registry: 31th Official Report of the Heart Failure Association of the Spanish Society of Cardiology 

      González-Vílchez, Francisco; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Gómez-Bueno, Manuel; González-Costello, José; Pérez-Villa, Félix; Delgado-Jiménez, Juan F.; Arizón-del-Prado, José M.; Sobrino-Márquez, José Manuel; Sousa-Casasnovas, Iago (Elsevier, 2020-08-14)
      [Abstract] Introduction and objectives. The present report describes the clinical characteristics and outcomes of heart transplants in Spain and updates the data to 2019. Methods. We describe the clinical characteristics ...
    • Steroids withdrawal during the first year after heart transplantation and its association with changes in renal function in a two year follow-up. RESTCO study 

      Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Gómez-Bueno, Manuel; González-Vílchez, Francisco; Lambert Rodríguez, José Luis; Fernández-Yáñez, Juan; Brossa-Loidi, Vicens; Lage-Gallé, Ernesto; Arizón-del-Prado, José M.; Almenar-Bonet, Luis; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; Muñiz, Javier; Delgado-Jiménez, Juan F. (Elsevier, 2014)
    • Temporal trends in the use and outcomes of temporary mechanical circulatory support as a bridge to cardiac transplantation in Spain. Final report of the ASIS-TC study 

      Barge-Caballero, Eduardo; González-Vílchez, Francisco; Almenar-Bonet, Luis; García-Cosío, María Dolores; González-Costello, José; Gómez-Bueno, Manuel; Castel-Lavilla, María Ángeles; Lambert-Rodríguez, José Luis; Martínez-Sellés, Manuel; Mirabet-Pérez, Sonia; De la Fuente-Galán, Luis; Hervás-Sotomayor, Daniela; Rangel-Sousa, Diego; Garrido-Bravo, Iris P.; Blasco-Peiró, Teresa; Rábago Juan-Aracil, Gregorio; Muñiz, Javier; Crespo-Leiro, María Generosa (Elsevier, 2022-11-09)
      [Abstract] Background: We aimed to describe recent trends in the use and outcomes of temporary mechanical circulatory support (MCS) as a bridge to heart transplantation (HTx) in Spain. Methods: Retrospective case-by-case ...
    • Utility of the IMPACT score for predicting heart transplant mortality: analysis on a contemporary cohort of the Spanish Heart Transplant Registry 

      Ortiz-Bautista, Carlos; Muñiz, Javier; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Sobrino-Márquez, José Manuel; Farrero-Torres, Marta; García-Cosío, M. Dolores; Díaz-Molina, Beatriz; Zegrí-Reiriz, Isabel; González-Vílchez, Francisco; Blázquez-Bermejo, Zorba; López Granados, Amador; Gómez-Bueno, Manuel; De la Fuente-Galán, Luis; Blasco-Peiró, Teresa; Garrido-Bravo, Iris P.; García-Romero, Elena; Rábago Juan-Aracil, Gregorio; García-Guereta, Luis; Delgado-Jiménez, Juan F. (Wiley, 2022-07-13)
      [Abstract] Introduction and objectives: The Index for Mortality Prediction After Cardiac Transplantation (IMPACT) score was derived and validated as a predictor of mortality after heart transplantation (HT). The primary ...